NAD⁺ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in every living cell, playing a central role in energy production, DNA repair, and cellular signaling. It is essential for metabolic function, acting as an electron carrier during ATP synthesis and serving as a substrate for sirtuins and PARPs—enzymes tied to aging, genomic stability, and stress response.
NAD⁺ levels decline with age, which has been linked to mitochondrial dysfunction, insulin resistance, and cognitive decline. As a result, NAD⁺ is being widely studied in models of aging, neurodegeneration, metabolic disorders, and cardiovascular health. Research into NAD⁺ supplementation—either directly or via precursors like NMN and NR—has shown promising effects on cellular health and resilience.
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